Saturday, October 30, 2010

The Real Secret of the Super Rich?

I found an interesting series of blog articles, starting here:


What caught my interest isn't so much that this reveals any surprising secrets, but that it is a reasonable mathematical analysis of the value of education and ability explained in simple terms. Simplified, but it makes a good point all the same.

I am less certain about the author's holistic politics, which are also interesting. However, I don't really have the time or energy right now to evaluate this properly. I do see a certain appeal in his mathematical approach to politics, but I remain skeptical that this approach can't be manipulated to fit specific goals, rather than the math driving the policy.
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Saturday, October 23, 2010

Science Fail #1

I'm borrowing the schtick of another blogger, who has not been actively lately. I hope he won't mind?
The idea of a "Science Fail" is to post a statement comment that fails in a completely self-explanitory way. Editing on my part is not allowed; each quote must fail on its own merits, or lack thereof. Go see Dirty Harry's Science Fail blog for many shining examples.

So what is this, Reality Show science? Leave to the Americans to get data by blowing something up or smashing something into something else. Keep this up and someday the Moon will be as livable as East Baghdad. (link to source)
If only Terraforming were that easy!

Found on Sciam.com
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Wednesday, October 13, 2010

Data Science, Science Data

Image Nature News
The latest Nature News has an article titled Computational Science: ... Error, describing the increasing difficulty scientists face as the computer programming required for research becomes more and more complex. I face a similar prob in my work. Much of the work I do requires a fair amount of database management as a precursor to the analysis. Most of this is basic SAS programming, with some tricky bits here and there, but it is all within reach of my programming skills. Most researchers don't have my programming skills (and with a BS in CoSci, many statisticians don't have my programming skills), which is one of the reasons they might come in for statistical help in the first place. Database management is an important skill for an applied statistician, but it is not my primary skill ("Dammit Jim, I've a statistician, not a bricklayer").

The point of this is not to blow my own horn, but that I have a set of skills for managing databases that is nearly independent of my statistical knowledge. The Nature News article points out the problems with programming skills, but the same problem exist with database skills: Some researchers don't understand the basics of recording data in an organized manner, and disorganized data can lead to as many problems as disorganized programming.

It is not too unusual for researchers to bring me data (typically in a spreadsheet), and sometime I spot specific problems that could be error in how they collected and recorded the data. This is fairly important, because if the data is wrong then my analysis will be too. Sometimes I can fix these errors for them, other times I have to have the researcher fix the problems, because it requires medical knowledge and familiarity with (or access to) the original data source to make the correction. Once these bugs have been ironed out, all it well and I do my statistical thing.

There is another sort of error though, and it is much more subtle. These are the errors in the data that don't really look like errors. When someone brings me their data and there is nothing obviously wrong, I probably don't question it, and proceed with the analysis. There are some common ways this might happen: cut & paste errors, "bad" sorts that scramble the data, inconsistency in data entry, all simple mistakes. Sometimes evidence of these errors shows up during my database management prep work or during the analysis itself. Obviously if a mistake is found, it gets fixed. However, if my experience with finding errors in the late stages of analysis is any indicator, then if seem likely that some of these errors are never found. The "garbage-in, garbage-out" principle applies, and some of the analyses I've produced were likely garbage, because the data was garbage.

The good news is this sort of error is unlikely to contribute much to the larger of body of scientific knowledge. By the nature of statistics (and with an assumption of some randomness) these subtle errors are unlikely to produce significant results, less likely to be in agreement with other published studies, and certainly unlikely to be verified by follow-up studies. The bad news is that some simple, perhaps even careless mistakes can ruin months or even years of research effort, which is a waste of effort.

Finally, this brings me that other set of skills: teaching. Whenever I have the opportunity to work with people who are starting off on new research projects, I try to teach the basic data-skills, the do's and don'ts, to help them get good data and do good research. Not everyone is interested in spreadsheets and databases, but it is not too hard to convince researchers that a little extra effort up front to get good data will pay dividends down the road when it comes to publications. It certainly pays me dividends when it comes to actually doing the statistical analysis - my primary skill - rather than spending hours (or days, or weeks) trying to track down what went wrong with the data, or unknowingly analyzing junk data.
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Wednesday, September 29, 2010

On the Rise of Science Comedy

I bring you Helen Pilcher of Nature.com on the rise of science comedy:
The comedic potential of particle accelerators or neurotransmission may not be obvious, but in the right hands they can be a recipe for mirth. And science has its own cast of wacky characters — from bongo-playing physicist Richard Feynman to gold-nosed astronomer and moose owner Tycho Brahe.
Moose owner? Now I'm, jealous! The full article also discusses the Ig Noble prizes, which are always a hoot.

And Shame! I haven't posted here for a month. What can I say, except that life is BUSY.
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Friday, August 27, 2010

Biostatistics vs. Lab Research

I had this same conversation just this morning!



Somehow I doubt the full humor of the situation will be apparent to most people, but this conversation occurs at my job on an occasional basis. A sample size of N=3 is a barest minimum for even a t-test, and on that basis alone probably isn't enough, but I'm willing to set that aside for the bigger issue, because it depends on the question.

It is a matter of the question asked. Not all experiments are the same, nor are all samples the same. In my conversation this morning, there was a basic misunderstanding of the sample unit. There was a sample size of N=3 in one group (treatment), and another group of 3 serving as a control. The problem (well one of the problems) was that the controls were not used as an independent group, but rather as a way to normalize each of the first 3. Instead of having two groups of 3 each, that we really had was a single group of 3 pairs of subjects (matched pairs). This lead to a few hours of trying to untangle What had been done versus what needed to be done. Frustrating, but then education is an important part of my job too.
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Wednesday, August 18, 2010

Thor's Hammer?

From POPSCI - Trapping Lightning in a block of acrylic.

There are many unusual things to see around Newton Falls, Ohio—the Wal-Mart with hitching posts for Amish buggies, the Army base with helicopters and tanks proudly arranged on hills—but I was here for the most unusual thing of all: the local Dynamitron. I was here to make frozen lightning.
Click over to POPSCI for the full story and a video. Cool stuff.

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